Âé¶¹´«Ã½Ó³»­

MENU
Sky View Through an Archway on Campus

Editing Help

Please reference the Faculty Profile Editing Guide if you have any questions or issues updating your profile. If you receive any error notices please contact webservices@fit.edu.

Jianhui Li

Assistant Professor | College of Engineering and Science: Biomedical Engineering and Science

Contact Information

li@fit.edu
(321) 674-7152
Olin Life Sciences Building Room 256




Expertise

Proteasome translocation, Autophagy, Yeast genetics, Cell signaling, Metabolic stress, Protein biochemistry, Biomolecular condensate

Educational Background

PhD, Virginia Tech, 2013-2017
MPhil, The Chinese University of Hong Kong?, 2010-2012
BS, Nanjing Agricultural University, 2006-2010

Professional Experience

Assistant Professor, Âé¶¹´«Ã½Ó³»­, 2023-Present

Graduate Faculty, Âé¶¹´«Ã½Ó³»­, 2023-Present

Postdoctoral Associate, Molecular Biophysics and Biochemistry, Yale University, 2017-2023

Current Courses

Virology (BIO4100 / BIO5573)

Immunology (BIO4201 / BIO5573)

Microbial Biotechnology (BIO5539 / BIO4150)

Experimental Design and Practice (BIO4100 / BIO5573)

Biological Research (BIO5995)

Biology Forum (BIO4990)

Undergraduate Research (BIO4991-4)

Selected Publications

  • Li J, Butcher C, VanderVen K, Fitz-Enz M, and Hochstrasser M (2025) AMPK alters proteasome phosphorylation status and prevents persistent proteasome condensates. .
  • VanderVen K, Butcher C, Fokine R, Li J (2025) Pep12 is important for proteasome microautophagy under low glucose conditions. .
  • Butcher C, VanderVen K, Li J (2025) Proteasome condensates repeatedly “contact and release” at the nuclear periphery during dissolution. .
  • Sultana S, Abdullah M, Li J, Hochstrasser M, Kachroo AH (2023) Species-specific protein-protein interactions govern the humanization of the 20S proteasome in yeast. 
  • Li J (2022) First person – Jianhui Li. 
  • Li J, Hochstrasser M (2022) Selective microautophagy of proteasomes is initiated by ESCRT-0 and is promoted by proteasome ubiquitylation.  (Featured in First Person interviews).
  • Ryu H-Y, Zhao D, Li J, Su D, Hochstrasser M (2020) Histone sumoylation promotes Set3 histone-deacetylase complex- mediated transcriptional regulation. 
  • Li J, Hochstrasser M (2020) Microautophagy regulates proteasome homeostasis. 
  • Li J, Breker M, Graham M, Schuldiner M, Hochstrasser M (2019) AMPK regulates ESCRT-dependent microautophagy of proteasomes concomitant with proteasome storage granule assembly during glucose starvation.  (Featured in Perspective articles).
  • Liu H*, Soyars C*, Li J*, Fei Q, He G, Peterson BA, Meyers BC, Nimchuk ZL and Wang X (2018) CRISPR/Cas9- mediated resistance to cauliflower mosaic virus.  (*co-first author).
  • Li J, Fuchs S, Zhang J, Wellford S, Schuldiner M, and Wang X (2016) An unrecognized function for COPII components in recruiting the viral replication protein BMV 1a to the perinuclear ER. 
  • Zhang J, Zhang Z, Chukkapalli V, Nchoutmboube JA, Li J, Randall G, Belov GA, and Wang X (2016) Positive-strand RNA viruses stimulate host phosphatidylcholine synthesis at viral replication sites. 
  • ?Yang X, Li J, Chen L, Louzada E, He J, and Yu W (2015) Stable mitotic inheritance of rice minichromosomes in cell suspension cultures. 
  • ?Zhang J, Li J, Garcia-Ruiz H, Bates PD, Mirkov TE, and Wang X (2014) A stearoyl-acyl carrier protein desaturase, NbSACPD-C, is critical for ovule development in Nicotiana benthamiana

Recognition & Awards

  • ?Casey DeSantis Florida Cancer Innovation Award, Florida Department of Health, 2026
  • Scholarship Excellence Award, PPWS, College of Agriculture and Life Sciences, Virginia Tech, 2017
  • Reginald and Phyllis Nelson Scholarship, College of Agriculture and Life Sciences, Virginia Tech, 2016